This systematic review was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Health care in the Philippines is provided through a mixed public-private system. Communicable diseases continue to be major causes of morbidity and mortality in the country. Philippine health status indicators show that the country lags behind most of Southeast and North Asia in terms of health outcomes. The population of the Philippines in 2015 was 100,981,437. The Philippines is an archipelago of 7,107 islands and is located in the western Pacific Ocean in Southeastern Asia. These gaps need to be identified since research interest and support for funding can only be achieved if scientists, decision makers and other stakeholders are able to understand developments related to the disease and recognize areas where more information is needed. The results of the review could provide an impression of local capacity and infrastructure for dengue research and help determine important knowledge gaps. The objective of the review is to better understand the trends in dengue research and the findings from these studies. We reviewed published studies on dengue research in the Philippines during the past 60 years. This could include basic laboratory research, the estimation of dengue seroprevalence and incidence the assessment of risk factors for severe disease the quantification of its economic burden the elucidation of local transmission and epidemiology the development of improved diagnostic tests or the evaluation of interventions. The focus of dengue research may vary widely. įindings from dengue studies could provide policy-makers with information needed for rational decision-making regarding dengue preventive and control efforts. The four dengue virus serotypes circulate in the country where the disease is predominantly reported among children.
Dengue continues to cause considerable concern in the country because of its widespread endemicity, the minimal success of vector control strategies, the possibility of severe disease caused by sequential infection by a different serotype, the potential for fatal outcomes and the consequent social and economic burden. In the early 1950’s, the disease was described in the Philippines as hemorrhagic fever or infectious acute thrombocytopenic purpura. Dengue is a mosquito-borne, acute febrile illness that is an important public health problem in tropical countries.
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